search
844.934.CARE
  • Show
    Health Library Explorer
    A B C D E F G H I J K L M N O P Q R S T U V W X Y Z A-Z Listings Contact Us
    A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
    Click a letter to see a list of conditions beginning with that letter.
    Click 'Topic Index' to return to the index for the current topic.
    Click 'Library Index' to return to the listing of all topics.

    Types of Muscular Dystrophy and Neuromuscular Diseases

    What are the different types of muscular dystrophy?

    Muscular dystrophy is a group of inherited diseases characterized by weakness and wasting away of muscle tissue, with or without the breakdown of nerve tissue. There are 9 types of muscular dystrophy, with each type involving an eventual loss of strength, increasing disability, and possible deformity.

    The most well known of the muscular dystrophies is Duchenne muscular dystrophy (DMD), followed by Becker muscular dystrophy (BMD).

    Listed below are the 9 different types of muscular dystrophy. Each type differs in the muscles affected, the age of onset, and its rate of progression. Some types are named for the affected muscles, including the following:

    Type

    Age at onset

    Symptoms, rate of progression, and life expectancy

    Becker

    adolescence to early adulthood

    Symptoms are almost identical to Duchenne, but less severe; progresses more slowly than Duchenne; survival into middle age. As with Duchenne, disease is almost always limited to males.

    Congenital

    birth

    Symptoms include general muscle weakness and possible joint deformities; disease progresses slowly; shortened life span.

    Duchenne

    2 to 6 years

    Symptoms include general muscle weakness and wasting; affects pelvis, upper arms, and upper legs; eventually involves all voluntary muscles; survival beyond 20s is rare. Seen in boys only. Very rarely can affect woman, who have much milder symptoms and a better prognosis.

    Distal

    40 to 60 years

    Symptoms include weakness and wasting of muscles of the hands, forearms, and lower legs; progression is slow; rarely leads to total incapacity.

    Emery-Dreifuss

    childhood to early teens

    Symptoms include weakness and wasting of shoulder, upper arm, and shin muscles; joint deformities are common; progression is slow; sudden death may occur from cardiac problems.

    Facioscapulohumeral

    childhood to early adults

    Symptoms include facial muscle weakness and weakness with some wasting of shoulders and upper arms; progression is slow with periods of rapid deterioration; life span may be many decades after onset.

    Limb-Girdle

    late childhood to middle age

    Symptoms include weakness and wasting, affecting shoulder girdle and pelvic girdle first; progression is slow; death is usually due to cardiopulmonary complications.

    Myotonic

    20 to 40 years

    Symptoms include weakness of all muscle groups accompanied by delayed relaxation of muscles after contraction; affects face, feet, hands, and neck first; progression is slow, sometimes spanning 50 to 60 years.

    Oculopharyngeal

    40 to 70 years

    Symptoms affect muscles of eyelids and throat causing weakening of throat muscles, which, in time, causes inability to swallow and emaciation from lack of food; progression is slow.

    What are other neuromuscular diseases?

    Spinal muscular atrophies:

    • Amyotrophic lateral sclerosis (ALS), or motor neuron disease

    • Infantile progressive spinal muscular atrophy

    • Intermediate spinal muscular atrophy

    • Juvenile spinal muscular atrophy

    • Adult spinal muscular atrophy

    Inflammatory myopathies:

    • Dermatomyositis

    • Polymyositis

    • Inclusion body myositis

    Diseases of peripheral nerve:

    • Charcot-Marie tooth disease

    • Dejerine-Sottas disease

    • Friedreich's ataxia

    Diseases of the neuromuscular junction:

    • Myasthenia gravis

    • Lambert-Eaton syndrome

    • Botulism

    Metabolic diseases of the muscle:

    • Acid maltase deficiency

    • Carnitine deficiency

    • Carnitine palmityl transferase deficiency

    • Debrancher enzyme deficiency

    • Lactate dehydrogenase deficiency

    • Mitochondrial myopathy

    • Myoadenylate deaminase deficiency

    • Phosphorylase deficiency

    • Phosphofructokinase deficiency

    • Phosphoglycerate kinase deficiency

    Less common myopathies:

    • Central core disease

    • Hyperthyroid myopathy

    • Myotonia congenita

    • Myotubular myopathy

    • Nemaline myopathy

    • Paramyotonia congenita

    • Periodic paralysis-hypokalemic-hyperkalemic

    Online Medical Reviewer: Shelat, Amit, MD
    Online Medical Reviewer: Turley, Raymond Kent, BSN, MSN, RN
    Date Last Reviewed: 5/1/2018
    © 2000-2019 The StayWell Company, LLC. 800 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.
    Powered by StayWell
    About StayWell | StayWell Disclaimer